Researchers at Sanford-Burnham Medical Research Institute, Human Biomolecular Research Institute and ChemRegen, Inc. managed to do a search of molecules that modify stem cells to heart cells after doing research for eight years. They used a robot to screen large collections of such drugs and chemicals found ITD-1, a molecule that can be used to generate unlimited numbers for heart cells from stem cells.
"Heart disease is the leading cause of death worldwide. Since we can not replace the diseased heart muscle, an irreversible condition causes a decrease in cardiac function resulting in death. The only effective way to replace the diseased heart muscle cell is the heart transplant cardiomyocytes overall. Well, with this invention are expected to create new heart muscle from stem cells. step is far more efficient than a heart transplant, "said Director of Sanford-Burnham's muscle Development and Regeneration Program Mark Mercola.
cardiac signal
Mercola and his team hunt for a signal to stimulate the heart for 15 years in embryos and stem cells. They use sophisticated robots to test chemicals when added to the stem cells generate cardiomyocytes. The result is a win is a compound of ITD-1, is useful to improve the differentiation of stem cells in the diseased heart.
At some point become the basis of stem cell therapy treatment of heart disease by limiting the spread of the scar and to the formation of new muscle. Mercola and his team currently working with biotechnology companies ChemRegen, Inc. to develop the ITD-1 one day become a commercial drug that can treat patients with heart disease.
THERAPY of stem cells offer a radically new treatment for heart disease. The team of researchers from the United States made great strides for the treatment of cardiovascular diseases with the discovery of molecules that can turn stem cells into heart cells.
